منابع مشابه
Comment on: Antifungal therapy: drug-drug interactions at your fingertips.
The Information Age has revolutionized the ability of healthcare professionals (HCPs) to oversee a substantial body of clinically relevant information literally at one's fingertips. In the field of clinical pharmacology, this may be particularly useful for managing drug-drug interactions (DDIs). A thorough understanding of the underlying mechanisms of DDIs allows the HCP to predict such interac...
متن کاملAntifungal drug resistance.
The increasing incidence of invasive fungal infections is the result of many factors, including an increasing number of patients with severe immunosuppression. Although new drugs have been introduced to combat this problem, the development of resistance to antifungal drugs has become increasingly apparent, especially in patients who require long-term treatment or who are receiving antifungal pr...
متن کاملAntifungal photodynamic therapy.
In photodynamic antimicrobial chemotherapy (PACT), a combination of a sensitising drug and visible light causes selective destruction of microbial cells. The ability of light-drug combinations to kill microorganisms has been known for over 100 years. However, it is only recently with the beginning of the search for alternative treatments for antibiotic-resistant pathogens that the phenomenon ha...
متن کاملCombination antifungal therapy.
Combination Antifungal Therapy Melissa D. Johnson,* Conan MacDougall, Luis Ostrosky-Zeichner, John R. Perfect, and John H. Rex Departments of Medicine, and Pharmacy, Duke University Medical Center, Durham, and Campbell University School of Pharmacy, Buies Creek, North Carolina; Division of Infectious Diseases, Department of Internal Medicine, Center for the Study of Emerging and Re-emerging Pat...
متن کاملEfflux-mediated antifungal drug resistance.
Fungi cause serious infections in the immunocompromised and debilitated, and the incidence of invasive mycoses has increased significantly over the last 3 decades. Slow diagnosis and the relatively few classes of antifungal drugs result in high attributable mortality for systemic fungal infections. Azole antifungals are commonly used for fungal infections, but azole resistance can be a problem ...
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ژورنال
عنوان ژورنال: Revista do Instituto de Medicina Tropical de São Paulo
سال: 1991
ISSN: 0036-4665
DOI: 10.1590/s0036-46651991000300015